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Allergic Reactions



The allergic reaction is triggered by an antibody called immunoglobulin E (usually called IgE). These antibodies are the chemical signals that set off an acute (sudden) allergic reaction. Allergic reactions types include:

Immediate hypersensitivity or IgE mediated immunological reaction (type I):

Involving IgE the most common allergic reaction and has the most clearly understood mechanism and usually happen within minutes.

Non-IgE mediated immunological reaction to food hypersensitivity (type II):

is not clear. IgE antibody react with the cell membrane or an antigen associated with the cell membrane and the time for the symptoms to take place occur within hours to several days.

Antigen-antibody complex (type III):

may have a role in several foods related inflammatory diseases (colitis, enteritis with bleeding, malabsorptive disorders, ulceration, chronic pneumonitis)

Cell-mediated hypersensitivity (type IV):

may have a role in celiac disease, inflammatory bowl disorders such as ulcerative colitis.

As for type I, anaphylactic shock is usually occur which is severe allergic reaction. it is life treating reaction and the blood pressure drops as the airways narrows. this condition is dangerous and can lead to death.

How to treat the anaphylactic shock?

Epinephrine auto-injector (EpiPen) then visit the ER immediately to receive antihistamine and corticosteroid.

As for type II, the reactions can vary by system, from gastrointestinal to respiratory; gastrointestinal reactions are the most common reactions. the following table include most common syndromes and foods causing the allergy:


Can foods allergy be outgrown?

Milk allergy often outgrown in children by age 5, however; some children may suffer from allergy for lifelong. Also, peanuts, tree nuts, and shellfish are often lifelong allergies.

Credits: BMC journal

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